The JPost is referring to a study in NEJM which has taken a blood sample from ~1600 people in the Spanish and Italian epicentres of early Covid-19 meltdown. At some stage in every patient's treatment bloods were taken and while they were routine checking for creatinine, serum albumin and alkaline phosphatase they also had to check ABO blood groups in case anyone needed a transfusion. I've written about ABO blood groups before in the context of priority - paternity - geography - history - disease association. But my [slightly delayed] response was ooooo data and I scooted off to the NEJM to download Supplementary Appendix 8 which contains the raw counts and %s for ABO in various geographic and medical-severity bins.
proto-Indo-European PIE and their blood groups look like a sore thumb (mostly Rhesus diffs it must be said). As a side-swipe, note the different colours on the map [R] for Lombardy and NE Spain where most of the Covid-sick in the study came from.
I scraped the pooled ABO / Covid-serious cases / Disease free controls from Appendix 8:
Chi.Sq test. The base-line differences are highly significant (Chi.Sq = 27; df 3; p < 0.001) with their being more A alleles in Spain and fewer B. Which is grand because we effectively have two different parallel experiments which both reveal the same skew: you are about 50% more likely to finish up on a ventilator if you are blood group A and a third less likely to do so if you are Group O. This is the odds ratio OR: [explained] (a/c)/(b/d) = 1.54 for Italy (it's 1.31 for Spain) where
- a = ++ number of ventilated As = 388
- b = +- number of unsick As = 451
- c = -+ number of ventilated (AB+B+O) = 43 + 91 + 313
- d = -- number of unsick (AB+B+O) = 50 + 163 + 591
really small titanium Captain America shield.
It's a bit like my analysis is Statins. They have demonstrable, statistically significant effect on lowering cholesterol and so will prevent heart attacks. But the number needed to treat NNT for statins is more than 100! 100 people have to be taking statins for 1 to not have a coronary infarction. Statins have wild side-effects in some people and will cost you (or the beneficent HSE) a chunk of money. You'd be better off changing your diet, getting off your couch, de-stressing and being more socially engaged. But these take effort, statins just need a small glass of water.
On Covid-19, you can't change your blood group but you'd be spiffin' bonkers to think
I R O, I R OK, I can share spittle with randomers